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Last updated: 2019/6/16
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校园足球比赛作文600字:CytoQuest? CR - 循環罕見細胞陽性富集與收集系統

幼儿园足球教案 www.vxwgk.com 亞諾法的 CytoQuest? CR 是用于循環罕見細胞 (CRC) 捕捉、計數、富集和收集的系統。在轉化和臨床研究中的三個主要CRC亞型為 循環腫瘤細胞 (CTC)、循環祖細胞 (CPC) 和循環胎兒細胞 (CFC)。CRC在市場是否能被采用,取決于下列因素: 1.有效和可重現的識別 2. 單細胞分離 3. 高純度富集及具活性的細胞,而使用的試劑和耗材上則需達GMP等級的規格。

CytoQuest? CR 技術藉由SCx? 樣品室、抗體披覆之納米結構晶片和 TCx? 溫控裝置來提供多種捕捉與富集的功能。SCx? 樣品室配備低沾粘性管線和外掛微震動器,以此特殊設計有效地將預處理的血樣輸送到納米結構芯片。HBx?微混合器以人字型微結構管道干攪層流并攪動以促成細胞和芯片接觸。CytoChipNano 是鏈霉親和素納米芯片,可以捕捉 CRC并通過激光顯微分離或顯微操作進行單細胞的收集。CytoChipNano CR 是額外多了熱敏涂層的鏈霉親和素納米芯片,可配合調控溫度的TCx?裝置來達成捕捉和釋放CRC的效果。

以循環罕見細胞的特定表面生物標記物為靶的單克隆抗體也可依需求靈活替換,以因應細胞進展中伴隨的生物標記物變化。由此可得到高純度和具活性的細胞,應用于下游蛋白質表征、基因分析和細胞檢測。細胞計數是目前唯一通過 FDA 批準的CTC應用,用于乳腺癌、前列腺癌和結腸直腸癌的預后指標。相較之下,有效分離單細胞和富集CRC將為臨床診斷和制藥行業的應用開辟新的道路。


 
Catalog # : M0014-04
Price: Please Inquire
Regulatory Status : RUO & CE-IVD (EU only)
 
Subtypes of CRCs

  • Circulating Tumor Cells (CTCs)
  • Circulating Progenitor Cells (CPCs)
  • Circulating Fetal Cells (CFCs)
 
Applications of CTCs

Protein Characterizations
  • Immunofluorescence
  • Immuno-Rolling Circle Amplification (iRCA)
Gene Analysis
  • Fluorescent In Situ Hybridization (FISH)
  • Polymerase Chain Reaction (PCR)
      Gene Amplifications (GAs)
      Somatic Mutations (SMs)
      Single Nucleotide Polymorphisms (SNPs)
  • Comparative Genomic Hybridization (CGH)
      Copy Number Variants (CNVs)
  • Next Generation Sequencing (NGS)
Cell Assays
  • Primary cell line construction
  • Compound screening
 
Advantages of CytoQuest? CR Platform

Integrated system
  • Bottle reservoir
  • Fluidic handler
  • SCx™ spiral chamber
  • TBx? tension balancer
  • Coupler
  • HBx™ micromixer
  • Chip receptor
  • TCx™ thermal chuck
  • Touch user interface
Antibody-based, cell capture
  • Cell enumeration (CytoChipNano)
  • Single cell isolation (CytoChipNano)
  • Thermal cell release (CytoChipNano CR)
 

CytoQuest™ CR                     

Buffer Reservoir
Bottle Reservoir
Fluidic
Fluidic Handler
Chamber
SCx? Spiral
Chamber
Spiral Chamber Holder
Spiral Chamber Holder
 
TBx? Tension Balancer
TBx? Tension Balancer
Coupler
Coupler
Chip Receptor
Chip Receptor
Micromixer
HBx™ Micromixer
 
CytoChipNano
CytoChipNano
CytoChipNano CR
CytoChipNano
CR
TCx? Thermal Chuck
TCx? Thermal
Chuck
Chip Opener
Chip Opener
 
Temperature
Temperature Display
QR Code Scanner
QR Code Scanner
Power On LED
Power On LED
Touch User Interface
Touch User Interface
 
 
Hardware General Specifications

Dimensions: 565.06mm(h) x 340.8mm(d) x 271.8mm(w)
Weight: 18 kg
Power: Fluidic Handler: 100-240VAC, 50/60Hz,1.6A
Thermal Controller: 100-240VAC, 50/60Hz, 4.0A
Replace Fuse: Fluidic Handler: 1.6A(Peak)/250V
Thermal Controller: 4A (Peak)/250V
Operating Temperature: 60°F to 104°F (15°C to 40°C)
Programable Thermo Control Profile: 4-40°C, Variable Time Span
 
Hardware Environmental Specifications

Storage Temperature: -5°F to 158°F (-20°C to 70°C)
Operation Altitude: Up to 2000m
Operation Environment: For indoor use
Operating Humidity: 20% to 90% Relative Humidity, Non-Condensing
Storage Humidity: 20% to 95% Relative Humidity, Non-Condensing
 
Software Specifications

Scanner Function: Scanning Capability to Read QR Code/Barcode
Status Display: Progress and Fluid Handling
System Clean: Prime and Clean
Report Generation: Print and Export File
 
Touchscreen Laptop Specifications

Operating System: Windows 7/8/10 (32-bit and 64-bit)
Processor: Pentium III/Celeron 866 MHz or Equivalent
Memory: 1GB Minimum (2GB Recommended)
Free Disk Space: 4GB
Interfaces/USB Ports: USB 2.0 Port*1
 
 
Chip

Cell Enumeration
  • CytoChipNano Combo Pack (Catalog #: KA4440)
  • CytoChipNano (Catalog #: U0095)
  • SCx? Spiral Chamber (Catalog #: U0314)
  • Plugs (Catalog #: KA4441)
 
Single Cell Isolation
  • CytoChipNano Combo Pack (Catalog #: KA4440)
  • CytoChipNano (Catalog #: U0095)
  • SCx? Spiral Chamber (Catalog #: U0314)
  • Plugs (Catalog #: KA4441)
 
Capture & Release
  • CytoChipNano CR Combo Pack (Catalog #: KA4862)
  • CytoChipNano CR (Catalog #: U0096)
  • SCx? Spiral Chamber (Catalog #: U0314)
  • Plugs (Catalog #: KA4441)
 
 
Bioreagent

Circulating Epithelial Cells
  • CytoQuest? EpCAM PanCK CD45 Antibody Kit (Catalog #: KA4439)
  • CytoQuest? EpCAM PanCK CD45 Antibody Release Kit (Catalog #: KA4863)
  • CytoQuest? EpCAM PanCK CD45 Mouse Antibody Kit (Catalog #: KA4576)
  • CytoQuest? EpCAM PanCK CD45 PLS3 EMT Antibody Kit (Catalog #: KA4586)
  • CytoQuest? EpCAM PanCK CD45 CSV EMT Antibody Kit (Catalog #: KA4817)
  • CytoQuest? EpCAM PanCK CD45 CD44v9 EMT Antibody Kit (Catalog #: KA4897)
  • CytoQuest? Epithelial Cell Solution (Catalog #: KA3967)
 
Circulating Tumor Cells
  • CytoQuest? Universal Circulating Tumor Cell CSV CSV CD45 Antibody Kit (Catalog #: KA4818)
  • CytoQuest? CSV CSV CD45 Antibody Release Kit (Catalog #: KA4959)
  • CytoQuest? Checkpoint Circulating Tumor Cell CSV CSV CD45 PD-L1 Antibody Kit (Catalog #: KA4968)
  • CytoQuest? Glioblastoma Multiforme CSV CSV CD45 EGFRvIII Antibody Kit (Catalog #: KA4906)
  • CytoQuest? Glioblastoma Multiforme CSV CSV CD45 GFAP Antibody Kit (Catalog #: KA4905)
  • CytoQuest? Lung Cancer CSV CSV CD45 TTF1 Antibody Kit (Catalog #: KA4960)
  • CytoQuest? Breast Cancer CSV CSV CD45 ER Antibody Kit (Catalog #: KA4961)
  • CytoQuest? Neuroblastoma CSV CSV CD45 GD2 Antibody Kit (Catalog #: KA4962)
  • CytoQuest? Liver Cancer CSV CSV CD45 ASGPR Antibody Kit (Catalog #: KA4963)
  • CytoQuest? Liver Cancer ASGPR PanCK CD45 Antibody Kit (Catalog #: KA4573)
  • CytoQuest? Pancreatic Cancer CSV CSV CD45 PDX1 Antibody Kit (Catalog #: KA4964)
  • CytoQuest? Colorectal Cancer CSV CSV CD45 CDX2 Antibody Kit (Catalog #: KA4965)
  • CytoQuest? Choriocarcinoma HLA-G PanCK CD45 Antibody Kit (Catalog #: KA4530)
  • CytoQuest? Prostate Cancer CSV CSV CD45 PSMA Antibody Kit (Catalog #: KA4966)
  • CytoQuest? Prostate Cancer CSV CSV CD45 AR-V7 Antibody Kit (Catalog #: KA4967)
  • CytoQuest? Sarcoma CSV CSV CD45 Antibody Kit (Catalog #: KA4864)
 
Circulating Cancer Stem Cells
  • CytoQuest? Universal Cancer Stem Cell CSV CSV CD45 Antibody Kit (Catalog #: KA4819)
  • CytoQuest? Glioblastoma Multiforme CSV CD45 DBA Antibody Kit (Catalog #: KA4908)
  • CytoQuest? Lung Cancer CSV CSV CD45 CD133 Antibody Kit (Catalog #: KA4969)
  • CytoQuest? Renal Cancer B7-H3(CD276) CD105 CD45 Antibody Kit (Catalog #: KA4577)
 
Circulating Fetal Cells
  • CytoQuest? Extravillous Trophoblast HLA-G TBA CD45 Antibody Kit (Catalog #: KA4515)
  • CytoQuest? Circulating fNRBC CD71 CD71 GPA CD45 Antibody Kit (Catalog #: KA4970)
 
Cell-Surface Vimentin (CSV) Monoclonal Antibody, Clone 84-1
  • Cell-Surface Vimentin (CSV) monoclonal antibody, clone 84-1 (Catalog #: H00007431-M08)
  • Cell-Surface Vimentin (CSV) monoclonal antibody, clone 84-1 (APC) (Catalog #: H00007431-MA08)
  • Cell-Surface Vimentin (CSV) monoclonal antibody, clone 84-1 (Biotin) (Catalog #: H00007431-MB08)
  • Cell-Surface Vimentin (CSV) monoclonal antibody, clone 84-1 (FITC) (Catalog #: H00007431-MF08)
  • Cell-Surface Vimentin (CSV) monoclonal antibody, clone 84-1 (PE) (Catalog #: H00007431-MP08)
  • Cell-Surface Vimentin (CSV) monoclonal antibody, clone 84-1 (Texas Red) (Catalog #: H00007431-MT08)
 
Blockers, Fixative, Inhibitor and Picking
  • FcR Blocking Reagent (Catalog #: U0318)
  • Special Fixative (Catalog #: U0377)
  • Staining Blocker (Catalog #: U0330)
  • Single Cell Picking Kit (Catalog #: KA4578)
  • Leukocyte Aggregation Inhibitor (Catalog #: U0386)
 
Point Mutations, Gene Amplification, and Translocation mutaFISH? Probes and Accessory Kits
  • mutaFISH? ACTBwt RNA Probes (Catalog #: FP0013)
  • mutaFISH? AR-V7 ARwt RNA Probes (Catalog #: FP0004)
  • mutaFISH? BRAF V600E V600wt RNA Probes (Catalog #: FP0011)
  • mutaFISH? CEP1wt CEP7wt CEP8wt CEP17wt DNA Probes (Catalog #: FP0009)
  • mutaFISH? CEP1wt DNA Probes (Catalog #: FP0008)
  • mutaFISH? CEP7wt DNA Probes (Catalog #: FP0006)
  • mutaFISH? CEP8wt DNA Probes (Catalog #: FP0005)
  • mutaFISH? CEP17wt DNA Probes (Catalog #: FP0007)
  • mutaFISH? CK7wt RNA Probes (Catalog #: FP0027)
  • mutaFISH? CK9wt RNA Probes (Catalog #: FP0028)
  • mutaFISH? CK19wt RNA Probes (Catalog #: FP0029)
  • mutaFISH? CK20wt RNA Probes (Catalog #: FP0030)
  • mutaFISH? c-Mycwt RNA Probes (Catalog #: FP0015)
  • mutaFISH? CXCL9 RNA Probes (Catalog #: FP0025)
  • mutaFISH? CXCL10 RNA Probes (Catalog #: FP0026)
  • mutaFISH? EGFRwt RNA Probes (Catalog #: FP0023)
  • mutaFISH? EGFR T790M T790wt RNA Probes (Catalog #: FP0001)
  • mutaFISH? EGFR L858R L858wt Ex19wt RNA Probes (Catalog #: FP0002)
  • mutaFISH? EML4wt ALKwt RNA Probes (Catalog #: FP0014)
  • mutaFISH? ERCC1wt RNA Probes (Catalog #: FP0024)
  • mutaFISH? HER2wt RNA Probes (Catalog #: FP0022)
  • mutaFISH? HER2wt DNA Probes (Catalog #: FP0010)
  • mutaFISH? HLA-ABCwt RNA Probes (Catalog #: FP0021)
  • mutaFISH? IDH1 R132H R132wt IDH2 R172K R172wt RNA Probes (Catalog #: FP0012)
  • mutaFISH? IFNGwt RNA Probes (Catalog #: FP0031)
  • mutaFISH? KRAS G12wt G13wt RNA Probes (Catalog #: FP0017)
  • mutaFISH? MAMwt RNA FISH Probes (Catalog #: FP0020)
  • mutaFISH? MYCNwt DNA Probes (Catalog #: FP0003)
  • mutaFISH? PD-L1wt RNA Probes (Catalog #: FP0019)
  • mutaFISH? PSAwt RNA Probes (Catalog #: FP0018)
  • mutaFISH? TERTwt RNA Probes (Catalog #: FP0016)
  • mutaFISH? RNA Accessory Kit (Catalog #: KA4915)
  • mutaFISH? DNA Accessory Kit 1 for Cells (Catalog #: KA4916)
  • mutaFISH? DNA Accessory Kit 2 for Cells (Catalog #: KA4928)
 
Gene Amplification, Translocation, and Split FISH Probes
  • ACTN4 DNA Probe (Catalog #: DF0001)
  • AR/CENXp FISH Probe (Catalog #: FG0163)
  • BRCA1/CEN17q FISH Probe (Catalog #: FG0069)
  • CD274 (PD-L1)/CEN9q FISH Probe (Catalog #: FG0160)
  • CEP8 (R6G) FISH Probe (Catalog #: FC0197)
  • EGFR/CEN7p FISH Probe (Catalog #: FG0114)
  • EML4/ALK Translocation FISH Probe (Catalog #: FT0009)
  • ERBB2 (HER2)/CEN17q FISH Probe (Catalog #: FG0166)
  • ERG Split FISH Probe (Catalog #: FS0008)
  • MYC/CEN8q FISH Probe (Catalog #: FG0117)
  • p53/CEN17q FISH Probe (Catalog #: FG0011)
  • PLS3/CENXp FISH Probe (Catalog #: FG0164)
  • PRDM14 FISH Probe (Catalog #: FG0165)
  • PTEN/CEN10p FISH Probe (Catalog #: FG0019)
  • TOP2A/CEN17q FISH Probe (Catalog #: FG0119)
 
Cell Staining Dyes
  • Calcein AM (Catalog #: U0333)
  • DAPI (Catalog #: U0331)
  • Hoechst 33342 (Catalog #: U0334)
  • Propidium Iodide (Catalog #: U0332)
 
 
Accessory

  • Bottle and Tubing Pack (Catalog #: KA4442)
  • CytoQuest? Single Cell Micromanipulator Set (Catalog #: KA4584)
  • Cell Picking Microscope, Camera, and Software (Catalog #: MR0005)
  • Scanning Microscope and CytoView? Software (Catalog #: M0019)
  • Na-Heparin Blood Collection Tube (Catalog #: MR0007)
  • ACD-A Blood Collection Tube (Catalog #: MR0008)
 
 
Application Notes

Capture and Isolation of EpCAM and CD133 Positive Cells in Peripheral Blood of Non-Small Cell Lung Cancer Patients
Detection of Circulating Tumor Cells in Cholangiocarcinoma Patients
EpCAM CK Positive Circulating Tumor Cells and B7-H3 CD105 Positive Cancer Stem Cells in Clear Cell Renal Cell Carcinoma
Circulating Tumor Cells as Metastatic Biomarker in Oral Squamous Cell Carcinoma
Prenatal Detection of Fetal Trophoblasts in Maternal Circulation
Circulating Epithelial Cells in Dialysis Patient with Acquired Cystic Kidney Disease
Androgen Receptor Gene Amplification in Circulating Tumor Cells of Metastatic Castration-Resistant Prostate Cancer Patient
PSMA vs EpCAM Antibody Capture of Circulating Tumor Cells in Metastatic Castration-Resistant Prostate Cancer Patient
Antibodies Targeting HLA-G and PanCK for Capture and Identification of Circulating Choriocarcinoma Cells
Antibodies Targeting ASGPR and PanCK for Capture and Identification of Circulating Hepatocellular Carcinoma Cells
Plastin-3 Transformed Circulating Tumor Cells in Hepatic Portal Vein of Pancreatic Cancer Patient for Predicting Liver Metastasis
Cell-Surface Vimentin as Novel Epithelial-Mesenchymal Transition and Cancer Stem Cell Biomarkers for Pancreatic Cancer Circulating Tumor Cells
Cell-Surface Vimentin Transformed EMT CTCs and CSCs in Metastatic Castration-Resistant Prostate Cancer
Cell-Surface Vimentin and Pan Cytokeratin Positive Circulating Tumor Cells in Pleural Effusion of Lung Adenocarcinoma Patient
CDX2 Intestinal-Specific Expression in Circulating Tumor Cells of Metastatic Colorectal Adenocarcinoma Patient
Detection of CD44v9 EMT and CSC Protein Biomarker in Circulating Tumor Cells of Castration-Resistant Prostate Cancer Patient
GFAP and EGFRvIII Detection of Glioblastoma Multiforme Circulating Tumor Cells Captured by Cell-Surface Vimentin Antibody
Isolation of DBA Positive Circulating Cancer Stem Cells in Glioblastoma Multiforme
Compare EpCAM PanCK and CSV CSV Antibody Capture and Detection of Ovarian Papillary Serous Cystadenocarcinoma
Cell-Surface Vimentin Antibody for Postive Microfluidic Enrichment and Enumeration of Neuroblastoma CTCs and DTCs
PD-L1 Expression in Cell-Surface Vimentin Positive Circulating Tumor Cells of Colorectal Cancer Patient
EGFR L858R and Ex19wt In Situ mutaFISH? Detection in Circulating Tumor Cells of Non-Small Cell Lung Cancer

 

 

 
Publications

 


 
Support

Posters

 

CytoQuest? CR - Advanced Microfluidic System for Capture, Enumeration, Isolation, and Release of Circulating Tumor Cells
CytoQuest? CR - Diverse Clinical Applications of Circulating Tumor Cells in Cancers

 

 

Flyers

 

  CytoQuest? CR Powered by CSV Antibody and mutaFISH?
  CytoQuest? CR - Circulating Rare Cell Positive Enrichment & Retrieval System
  CytoQuest? CR Cell Kits & Bioreagents
  CytoQuest? CR & CytoView?
  CytoView? All-in-One Microscope with AI
  Epithelial-Mesenchymal Transition Antibody - Plastin-3
  Epithelial Stem Cell Monoclonal Antibodies - CD44 Variant Isoforms
  Cell-Surface Vimentin (CSV) Monoclonal Antibody
  Cell-Surface Vimentin (CSV) Monoclonal Antibody & Conjugates
  Cell-Surface Vimentin (CSV) Antibody Capture of Circulating Tumor Cells in Sarcoma Patients
  mutaFISH? - mutation-specific Fluorescence In Situ Hybridization
  mutaFISH? Probes
  FISH Probes vs mutaFISH? Probes
  Cancers & Cell-Surface Vimentin CTC Clinical Applications
  FDA-Approved Drugs in Cancer Immunotherapy
  Therapeutic Advances in Immune Checkpoint Inhibitors
  Circulating Tumor Cell (CTC) - Derived Xenografts (CDx)
  Single Cell Whole Genome Amplification & Sequencing

 

 

User Manual

 

  Please inquire

 

 

Software

 

  CytoQuest? CR Software v3.2.
  CytoQuest? CR Software v3.3.
  CytoQuest? CR Software v3.4.
        Download and decompress zip file to desktop. Run the executable file directly in the folder.

 

 

AbVideo?
  1. CytoQuest? CR Unpacking
  2. CytoQuest? CR Installation
  3. CytoQuest? CR Leucosep Preparation
  4. CytoQuest? CR Automated Leucosep Preparation
  5. CytoQuest? CR Capture Antibody Immobilization
  6. CytoQuest? CR Cell Capture
  7. CytoQuest? CR CytoView? All-in-One Imaging System
  8. CytoQuest? CR Cell Immunostaining
  9. CytoQuest? CR CTC mutaFISH?
  10. CytoQuest? CR CTC mutaFISH? - How It Works
  11. CytoQuest? CR CTC FISH
  12. CytoQuest? CR System Maintenance
  13. CytoQuest? CR SCx? Spiral Chamber Assembly - Dos and Don'ts
  14. CytoQuest? CR Plugs Assembly and CytoChipNano Placement - Dos and Don'ts
  15. CytoQuest? CR Bubbles & Microfluidics - Dos & Don'ts
  16. CytoQuest? CR CTC Capture and CTC FISH - Dos and Don'ts
  17. CytoQuest? CR Troubleshooting I (Access Required)
  18. CytoQuest? CR Troubleshooting II (Access Required)
  19. CytoQuest? CR Troubleshooting III (Access Required)
  20. CytoQuest? CR Troubleshooting IV (Access Required)

 

CytoQuest™ CR is a research-use-only (RUO) device and is also CE-IVD certified for EU requirement.


CytoQuest™ CR system, SCx™ spiral chamber, TBx? tension balancer, HBx™ micromixer, and TCx™ thermal control are trademarks and pending patents of Abnova Corporation.


Cell-Surface Vimentin (CSV) antibody is a pending MD Anderson patent which has been exclusively licensed to Abnova Corporation.


mutaFISH? is a pending trademark and patent of Abnova Corporation.

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